Determination of N-nitrosamine genotoxic impurities in metformin preparations by GC-MS/MS and investigation on generation mechanism of N-nitrosodimethylamine

WEN Song-song, NIU Chong, LIU Qi, ZHANG Lei, GUO Chang-chuan, XU Yu-wen, WANG Wei-jian

Chinese Journal of Pharmaceutical Analysis ›› 2022, Vol. 42 ›› Issue (8) : 1424-1432.

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Chinese Journal of Pharmaceutical Analysis ›› 2022, Vol. 42 ›› Issue (8) : 1424-1432. DOI: 10.16155/j.0254-1793.2022.08.16
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Determination of N-nitrosamine genotoxic impurities in metformin preparations by GC-MS/MS and investigation on generation mechanism of N-nitrosodimethylamine

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{{article.zuoZheEn_L}}. {{article.title_en}}[J]. {{journal.qiKanMingCheng_EN}}, 2022, 42(8): 1424-1432 https://doi.org/10.16155/j.0254-1793.2022.08.16

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